Sehlopha se kopaneng sa lipatlisiso se tsoang Sekolong sa Bongaka sa Harvard (HMS) le Sepetlele se Seholo sa MIT se re ba fihletse tokiso ea tlhahiso ea laser ea microdisk ba sebelisa mokhoa oa PEC etching, ho etsa mohloli o mocha oa nanophotonics le biomedicine "e tšepisang."
(Sephetho sa laser ea microdisk se ka fetoloa ka mokhoa oa PEC etching)
Masimong ananophotonicsle biomedicine, microdisklisebelisoa tsa laser'me li-lasers tsa nanodisk li fetohile tse tšepisangmehloli e khanyangle lipatlisiso. Lits'ebetsong tse 'maloa tse kang on-chip photonic communication, on-chip bioimaging, biochemical sensing, le quantum photon information processing, li hloka ho finyella tlhahiso ea laser ho fumana hore na wavelength le Ultra-narrow band e nepahetse. Leha ho le joalo, ho ntse ho le thata ho etsa li-laser tsa microdisk le nanodisk tsa bolelele bona bo nepahetseng ka bongata bo boholo. Mekhoa ea hona joale ea nanofabrication e hlahisa "randomness of disc diameter", e leng se etsang hore ho be thata ho fumana bolelele bo behiloeng ka laser mass processing le tlhahiso.Hona joale, sehlopha sa bafuputsi ba Harvard Medical School le Massachusetts General Hospital's Wellman Center bakeng saMeriana ea Optoelectronice thehile mokhoa o mocha oa ho qoelisa oa optochemical (PEC) o thusang ho lokisa ka nepo leqhubu la laser la microdisk laser ka ho nepahala ha subnanometer. Mosebetsi o hatisitsoe koranteng ea Advanced Photonics.
Etching ea photochemical
Ho ea ka litlaleho, mokhoa o mocha oa sehlopha o thusa ho etsa li-laser tsa li-micro-disk le li-laser tsa nanodisk tse nang le li-wavelengths tse nepahetseng, tse reriloeng esale pele. Senotlolo sa katleho ena ke ts'ebeliso ea PEC etching, e fanang ka mokhoa o sebetsang hantle le o qhekellang oa ho lokisa bolelele ba maqhubu a laser ea microdisc. Liphethong tse ka holimo, sehlopha se atlehile ho fumana li-microdisk tsa indium Gallium arsenide phosphating tse koahetsoeng ka silika holim'a sebopeho sa kholomo ea indium phosphide. Ka mor'a moo ba lokisa bolelele ba laser wavelength ea microdisk tsena hantle ho boleng bo boletsoeng ka ho etsa photochemical etching ka motsoako o hlapolotsoeng oa sulfuric acid.
Ba boetse ba fuputsa mekhoa le matla a li-etchings tse khethehileng tsa photochemical (PEC). Qetellong, ba fetiselitse lenane la microdisk-tuned microdisk holim'a polydimethylsiloxane substrate ho hlahisa likaroloana tse ikemetseng tsa laser tse nang le maqhubu a fapaneng a laser. Microdisk e hlahisoang e bonts'a bandwidth ea ultra-wideband ea laser emission, e nang lelaserkholomong e ka tlase ho 0.6 nm le karolo e ka thoko e ka tlase ho 1.5 nm.
Ho bula monyako oa lits'ebetso tsa biomedical
Sephetho sena se bula monyako oa lisebelisoa tse ngata tse ncha tsa nanophotonics le biomedical. Ka mohlala, li-laser tsa microdisk tse ikemetseng li ka sebetsa e le li-barcode tsa physico-optical bakeng sa lisampole tsa bioloji tse fapaneng, tse nolofalletsang ho ngola mefuta e itseng ea lisele le ho lebisa tlhokomelo ea limolek'hule tse khethehileng tlhahlobong ea multiplex. joalo ka organic fluorophores, matheba a quantum, le lifaha tsa fluorescent, tse nang le mehala e mengata ea tlhahiso. Kahoo, ke mefuta e ’maloa feela ea lisele tse khethehileng e ka ngoloang ka nako e le ’ngoe. Ka lehlakoreng le leng, khanya ea "ultra-narrow band light emission" ea "microdisk laser" e tla khona ho khetholla mefuta e mengata ea lisele ka nako e le 'ngoe.
Sehlopha se ile sa etsa liteko le ho atleha ho bonts'a likaroloana tsa laser tsa microdisk tse hlophisitsoeng hantle e le li-biomarker, tsa li sebelisa ho ngola lisele tse tloaelehileng tsa matsoele tsa epithelial MCF10A. Ka tlhahiso ea bona ea Ultra-wideband, li-lasers tsena li ka khona ho fetola biosensing, li sebelisa mekhoa e netefalitsoeng ea biomedical le optical joalo ka cytodynamic imaging, flow cytometry, le tlhahlobo ea multi-omics. Theknoloji e thehiloeng ho PEC etching e tšoaea tsoelo-pele e kholo ho li-laser tsa microdisk. Ho hlaka ha mokhoa ona, hammoho le ho nepahala ha subnanometer, ho bula menyetla e mecha bakeng sa lits'ebetso tse ngata tsa lasers ho nanophotonics le lisebelisoa tsa biomedical, hammoho le li-barcode bakeng sa palo e itseng ea lisele le limolek'hule tsa tlhahlobo.
Nako ea poso: Jan-29-2024